Biochemical Parameters in Patients with Diabetes and Urinary Tract Infection

Abstract

Urinary tract infections (UTI) are associated with complications of diabetes mellitus that is increasingly prevalent around the world. This cross-sectional study investigated the relationship among UTIs with biochemical markers and diabetes in 100 adult subjects with diabetes mellitus and UTIs. The purpose of the study was to determine the most uropathies, their antimicrobial susceptibility profile, and the effect of age on biochemical parameters and proteinuria. Urine cultures and standard biochemical assays were done. Data were analyzed using descriptive and analytical statistics and species of uropathies were identified using reliable diagnostic methods. At both sites, high confidence species identification of uropathies was attained, with Escherichia coli most observed followed by Klebsiella pneumoniae and Pseudomonas aeruginosa. Resistance patterns were diverse, and susceptibility testing were performed to help in choosing the most appropriate antibiotic. Age resulted in statistical significance of increased urea and creatinine levels which are associated with decreased renal function with age, there was also significant difference between age groups in the levels of proteinuria in their samples. Results showed that age has a good impact on diabetes, UTIs and biochemical parameters, such as renal function. Effective management and improved patient’s outcomes in diabetic patients with UTIs depend on close monitoring of glycemia and accurate identification of the Ur pathogen and appropriate antibiotic therapy.